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Blood Film - Blood is put on a slide so the cells can be observed using a microscope

Bone Marrow - Grainy red fluid that runs through the centre of the long bones and acts as the factory for our blood cells

Bone Marrow Aspirate - A sample of bone marrow (and sometimes a small 'core' of bone) removed using a needle for study using a microscope

Cannula / venflon - A small plastic tube inserted into a vein to give drugs, fluids or blood products to a patient

Full Blood Count (FBC) - A blood test providing a breakdown of your red and white cells and your platelets.



Granulocytes - White cells that fight off infections. When MPD patients have elevated white blood cell levels, treatment with drugs like hydroxycarbamide or interferon can reduce the count

Haematocrit (HCT) - Also known as Packed Cell Volume (PCV). A measure of the thickness or viscosity of blood caused by excess red blood cells

Haemoglobin - The oxygen-carrying pigment contained within red cells. Haemoglobin carries oxygen and carbon dioxide and contains iron. People with too much haemoglobin are polycythaemic. People with too little are anaemic

Heparin - A form of anticoagulant used to treat or prevent clots and sometimes given in pregnancy

Imatinib (Glivec, STI 571) - Designer drug used to treat chronic myeloid leukaemia
and forms of MPDs. Under trial to treat MF

JAK2- JAK2 is molecule inside our cells that sends growth messages to the cell. Many MPD patients have a mutation or change in JAK2

Leucocytes - Another term for white cells or granulocytes

Low Molecular Weight Heparin - A form of anticoagulant used to treat or prevent clots and sometimes given in pregnancy


Phlebotomy - Removal of blood

Plasma - Straw-coloured fluid through which our cells travel

Platelets - Cell fragments produced from megakaryocytes. Platelets stick together to form a clot when we bleed

Polycythaemia / Erythrocytosis - An increase in the number of red blood cells in the body

Red Blood Cells (RBCs) - Biconcave-shaped discs that contain haemaglobin, which carries oxygen and carbon dioxide to our bodies. Red blood cells survive for 120 days in the blood

Saline drip - Salty water occasionally used in the vein to replace the fluid lost while having a venesection. It is widely used for many other purposes and is known as a safe and versatile drug.


Thrombocytosis - A high platelet count

Venesection - The removal of 450mls of blood from your arm as a treatment for too many red blood cells. The method is the same as that of giving blood

White Blood Cells (WBC) - There are five types of white blood cells: lymphocytes, monocytes, neutrophils, eosinophils and basophils. These cells are our body's defence against infection. There are far fewer white cells than red cells in our bodies