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Myelofibrosis may not cause any obvious symptoms initially, and your doctor may discover you have this illness if you show abnormal blood cell counts on a blood test for something else.
People with MF may experience symptoms because of their low haemoglobin or anaemia. They may feel tired, lethargic, experience palpitations, have shortness of breath and occasionally chest pain. If platelet counts are low, patients may bruise easily or have bleeding problems. If white cell counts fall, infections occur.
People with MF have enlarged spleens. As the spleen grows, it can cause abdominal discomfort or pain, decreased appetite, a feeling of fullness in the abdomen after small meals and sometimes shoulder tip pain. Weight loss, sweats, fevers and fatigue also occur as the disease progresses.
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